首页> 外文OA文献 >Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities.

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Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities.

机译：具有均一聚糖（m3，G0，G2和a2）的糖基化改造的单克隆抗体使用化学酶学方法对FcγRIIIa和可变抗体依赖性细胞毒性活性具有不同的亲和力。

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Masaki Kurogochi; Masako Mori; Kenji Osumi; Mami Tojino; Shu-Ichi Sugawara; Shou Takashima; Yuriko Hirose; Wataru Tsukimura; Mamoru Mizuno; Junko Amano; Akio Matsuda; Masahiro Tomita; Atsushi Takayanagi; Shin-Ichiro Shoda; Takashi Shirai;
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1. Glycoengineered monoclonal antibodies using a chemoenzymatic approach and their affinities for Fc gamma RIIIa and variable antibody-dependent cellular cytotoxicities [J] . Shirai Takashi, Kurogochi Masaki, Mori Masako, Glycobiology. . 2015,第11期

机译：使用化学酶法的糖工程单克隆抗体及其对FcγRIIIa的亲和力和可变抗体依赖性细胞毒性
2. Terminal Effector CD8 T Cells Defined by an IKZF2(+)IL-7R(-) Transcriptional Signature Express Fc gamma RIIIA, Expand in HIV Infection, and Mediate Potent HIV-Specific Antibody-Dependent Cellular Cytotoxicity [J] . Naluyima Prossy, Lal Kerri G., Costanzo Margaret C., The Journal of Immunology: Official Journal of the American Association of Immunologists . 2019,第8期

机译：末端效应器CD8 T细胞由IKZF2（+）IL-7R（ - ）转录特征表达FCγRIIIA，在HIV感染中扩增，并介导有效的HIV特异性抗体依赖性细胞细胞毒性
3. Antibody-dependent cellular cytotoxicity and cytokine/chemokine secretion by KHYG-1 cells stably expressing FcγRIIIA [J] . KobayashiE., MotoiS., SugiuraM., Immunology Letters . 2014,第1期

机译：稳定表达FcγRIIIA的KHYG-1细胞的抗体依赖性细胞毒性和细胞因子/趋化因子分泌
4. Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3 G0 G2 and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities [O] . Masaki Kurogochi, Masako Mori, Kenji Osumi, -1

机译：使用化学酶法与均一的聚糖（M3G0G2和A2）进行糖工程改造的单克隆抗体对FcγRIIIa具有不同的亲和力并且抗体依赖性细胞的细胞毒性活性也不同
5. Transfection of FcγRIIIa (CD16) Alone Can Be Sufficient To Enable Human αβTCR T Lymphocytes To Mediate Antibody-Dependent Cellular Cytotoxicity [O] . Ollier, Jocelyn, Vivien, Régine, Vié, Henri, 2017

机译：单独转染FcγRIIIa（CD16）足以使人αβTCRT淋巴细胞介导抗体依赖性细胞毒性

Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities.

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